Research

Discover the standards and scientific rationale behind DESYB products
—from our core TRI+ Barrier System to targeted active ingredient concentrations.

SYSTEM

TRI+ Barrier

Foundational Skin Barrier Formulation Across All DESYB Products

Built on a shared foundation of Triple Ceramide Complex and Panthenol,
the TRI+ Barrier System pairs targeted active ingredients with barrier-reinforcing care.
Delivering clear functional results while keeping skin burden low, DESYB aims for a daily, effortless functional routine.

Triple Ceramide Complex

A ceramide complex inspired by the lipid structure of the skin barrier.
DESYB calibrates concentration levels based on formula texture and functional role.
* Toner 0.5% / Serum 2% / Cream 1%

Panthenol 2%

Panthenol is consistently formulated at 2% across all DESYB products
—a foundational active ingredient balanced for optimal hydration and skin comfort.
* Applied to All DESYB Products
Tone Balance Line
Renewal Firming Line

Targeted Functions

Targeted active ingredients are formulated into each line to address specific skin concerns.
Tone Balance focuses on brightening care, while Renewal Firming centers on targeted anti-aging care.
* Tone Care / Firming Care

Research

Ingredient Design

Research and data behind DESYB's ingredient design

Based on supplier test data and research on skin barrier structure, ceramide delivery, TEWL, and moisture retention,
we carefully formulated DESYB’s ingredient synergy and application strategy.

Research 01.

Triple Ceramide Complex

Intercellular lipids in the skin barrier are composed of ceramides, cholesterol, and fatty acids.
Inspired by this natural lipid structure, DESYB applies the Triple Ceramide Complex as a core barrier care foundation across all products.

※ Graphs and numerical data are compiled reference materials based on raw ingredient testing and do not represent clinical human trial results on finished products.
SKIN
BARRIER Reference lipid
balance
CERAMIDE 40%
FATTY ACID 30%
CHOLESTEROL 25%
OTHERS 5%
40 : 30 : 25 : 5 REFERENCE LIPID BALANCE

Skin Lipid Structure

Intercellular lipids in the skin barrier are primarily composed of ceramides, cholesterol, and fatty acids.
This lipid balance plays a key role in retaining moisture and protecting the skin against external stressors.
TRI+
BARRIER
COMPOSITION Skin-mimicking
lipid balance
CERAMIDE 25%
FATTY ACID 58%
CHOLESTEROL 8%
PHYTOSPHINGOSINE 8%
25 : 58 : 8 : 8 TRI+ BARRIER LIPID BALANCE

Triple Ceramide Complex

The Triple Ceramide Complex formulated in DESYB is a complex ingredient blending three types of ceramides, cholesterol, and fatty acids.
DESYB incorporates this skin-identical lipid composition as the shared core foundation of the TRI+ Barrier System.
100

Conventional
O/W emulsion

138

TRI+ Barrier
Complex

+38%

Compared to conventional O/W emulsion

Based on tape-strip assay, 0.5% Ceramide VI

Ceramide Delivery Comparison

According to supplier test data, DESYB’s Triple Ceramide Complex showed a 38% higher ceramide delivery index compared to standard O/W emulsions.
This reference data demonstrates the difference a barrier-optimized lipid structure makes in effective ceramide delivery.
27

일반 세라마이드
적용군

53

TRI+ Barrier
Complex

~2x

20시간 기준 TEWL 변화율

20시간 경과 후 TEWL 변화율 (Barrier Support Index)

TEWL Reduction Comparison

TEWL (Transepidermal Water Loss) is an indicator used to assess skin barrier condition by measuring moisture lost through the skin.
According to supplier test data, the group treated with DESYB’s Triple Ceramide Complex showed approximately 1.96 times higher TEWL reduction after 20 hours compared to the standard ceramide group.

Research 02.

Hypoallergenic & Primary Skin Irritation Test

Clear functional efficacy with minimal skin burden.

DESYB conducts primary skin irritation testing on all products,
achieving a 0.00 Skin Irritation Index for proven non-irritating formulations.

We balance high-performance active ingredients
with gentle, skin-conscious engineering.
Testing Institution Intertek
Participants 32 Korean adults

※ Individual results may vary.

View results by product Close product results

Skin irritation index by product

Renewal Firming Toner 0.00 Low irritation
Renewal Firming Serum 0.00 Low irritation
Renewal Firming Cream 0.00 Low irritation
Tone Balance Serum 0.00 Low irritation
Tone Balance Cream 0.00 Low irritation

Research 03.

Environmental Stressors & Skin Barrier Response

Dermatological studies on fine dust show
that a compromised skin barrier allows micro-pollutants to penetrate,
triggering reactive oxygen species (ROS) and inflammatory responses.

DESYB incorporates a foundational barrier-repair complex
across all products to maintain skin resilience against daily environmental aggressors.
Fine Dust Exposure
Penetration Through a Damaged Barrier
Oxidative Stress and Inflammatory Response

View the original research article

Research 04.

Dexpanthenol

Dexpanthenol (Panthenol) is a core ingredient formulated across
all DESYB products to optimize skin hydration and conditioning.

Research indicates that topical formulations containing
dexpanthenol help enhance stratum corneum moisture retention
and improve TEWL parameters.

MOISTURE & TEWL

Moisture Retention and TEWL

Skin hydration and TEWL-related parameters were evaluated
after repeated use of a panthenol-containing formulation.

View original research article Reduced TEWL and skin-protective effects

BARRIER RECOVERY

Barrier Recovery After External Irritation

A dexpanthenol-containing cream was applied to SLS-irritated skin
to evaluate barrier recovery and changes in skin condition.

View original research article Improved barrier recovery and hydration

Research 05.

Targeted Active Ingredient Architecture

DESYB pairs its foundational skin barrier complex with
targeted functional actives engineered for each specific product line.

TRI+ BARRIER

Tone Balance

Daily care for dull,
uneven-looking skin tone

Niacinamide 5%

Tranexamic Acid 3%

※ Functional cosmetic for skin brightening

TRI+ BARRIER

Renewal Firming

Daily firming care for loss of firmness
and rough-looking skin texture

Retinol 0.05%

Adenosine 0.04%

※ Functional cosmetic for wrinkle improvement

Product Formulation Standards

The DESYB Standard
Barrier First

We believe functional skincare is about long-term consistency rather than short-term intensity.

That is why DESYB formulates optimal concentrations of active ingredients alongside foundational barrier care in every single product.
Formula by Product

Toners, serums, and creams serve distinct functional roles and application steps.

Rather than repeating identical baseline formulas across every product,
DESYB customizes active ingredient ratios and texture profiles to optimize each step in your routine.
Sufficient Actives

We do not merely list active ingredients for marketing.

DESYB formulates functional actives at clinically effective concentrations, fully certified and reported under functional cosmetic standards.
Low Irritation

Functional efficacy must be clear, while skin burden remains minimal.

DESYB balances potent active concentrations with gentle, skin-conscious engineering,
achieving a proven 0.00 Skin Irritation Index in primary skin irritation testing on finished products.
Balance

Exceptional skincare cannot be defined by a single metric.

DESYB harmonizes functional efficacy, skin barrier reinforcement, and sensory texture to build daily, sustainable skincare routines.

Conclusion

Research Conclusion

Great skincare is not defined by a single ingredient, but by total architectural design.

Understanding skin biology,
selecting targeted actives aligned with product intent,
and engineering how each texture functions within a daily routine

DESYB unites barrier-first repair and functional engineering into one seamless routine.

RESEARCH BASIS.

DESYB's product formulation and Research content are grounded in the following reference data:

  • Guidelines from the Ministry of Food and Drug Safety (MFDS)
  • Technical dossiers from active raw material suppliers
  • Published peer-reviewed cosmetic research data
  • Finished product formulation architectures and full ingredient declarations (INCI)

VERIFICATION.

Verified scope within DESYB's products and technical documentation:

  • Functional cosmetic certifications and regulatory filings
  • Primary skin irritation test results (0.00 Skin Irritation Index)
  • Full ingredient declarations and active concentration levels per product
  • Test conditions and empirical metrics provided in supplier technical testing

NOTICE.

This page is designed to provide transparent technical rationale regarding DESYB's ingredient architecture and formulation standards.

External research references and raw material testing data do not constitute clinical human trial results on DESYB finished products,
nor do they guarantee identical outcomes for all skin types.